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咨询电话：15012456311利格列汀杂质对照品全套有哪些
深圳远扬化学技术有限公司可提供利格列汀坦项目申报所用全套杂质， 随货提供CoA证书，HNMR，MS，HPLC图谱，纯度符合申报要求，现货库存，交货及时，并可根据客户提供结构式进行利格列汀杂质定制合成。
利格列汀化合物是商品名为利格列汀片药物的主要成分，化学名为8-[（3R）-3-氨基-1-哌啶基]-7-(2-丁炔基-1)-3,7-二氢-3-甲基-1-[（4-甲基-2-喹唑啉基）甲基]-1H-嘌呤-2,6-二酮；临床上该化合物合成的药物是属于一种新的有效的选择性二肽基肽酶-4（DPP-4）抑制剂，可用于治疗2型糖尿病。
药理作用：利格列汀是二肽基肽酶4（DPP-4）抑制剂，DPP-4能够降解肠促胰岛素激素样多肽-1（GLP-1）以及葡萄糖依赖性促胰岛素多肽（GIP）。利格列汀能够升高活性肠促胰岛素激素的浓度，以葡萄糖依赖性的方式刺激胰岛素释放，降低循环中的胰高血糖素水平。
利格列汀杂质对照品全套有哪些
| 利格列汀 CAS号：668270-12-0 | Linagliptin |
| 利格列汀杂质1 | 7-(but-2-yn-1-yl)-8-((2-hydroxyethyl)amino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质2 | 2-((R)-3-aminopiperidine-1-carbonyl)-N-((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)benzamide |
| 利格列汀杂质3 CAS号：886588-63-2 | N-Phthalimide-linagliptin |
| 利格列汀杂质4 CAS号：1638744-06-5 | Linagliptin Impurity S |
| 利格列汀杂质5 | N1,N2-bis((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)phthalamide |
| 利格列汀杂质6 | (R)-2-((1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamoyl)benzoic acid |
| 利格列汀杂质7 | Linagliptin Diene Impurity |
| 利格列汀杂质8 | (Z)-8-bromo-7-(3-bromobut-2-en-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione |
| 利格列汀杂质9 | 8-bromo-1,7-di(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质10 | (R)-tert-butyl (1-(1,7-di(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate |
| 利格列汀杂质11 | (R)-8-(3-aminopiperidin-1-yl)-1,7-di(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质12 | 8-bromo-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione |
| 利格列汀杂质13 | (R)-tert-butyl (1-(3-methyl-7-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate |
| 利格列汀杂质14 | (R)-8-(3-aminopiperidin-1-yl)-3-methyl-7-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质15 CAS号：1446263-38-2 | (R)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-8-(piperidin-3-ylamino)-3,7-dihydro-1H-purine-2,6-dione |
| 利格列汀杂质16 CAS号：1803079-49-3 | (R)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)-2,2,2-trifluoroacetamide |
| 利格列汀杂质17 CAS号： 668270-11-9 | (S)-Linagliptin |
| 利格列汀杂质18 | 7-(but-2-yn-1-yl)-8-(dimethylamino)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质19 | N-(2-acetylphenyl)-2-(8-bromo-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetamide |
| 利格列汀杂质20 | (R)-tert-butyl (1-(1-(2-((2-acetylphenyl)amino)-2-oxoethyl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate |
| 利格列汀杂质21 | (R)-N-(2-acetylphenyl)-2-(8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-1-yl)acetamide |
| 利格列汀杂质22 | (R)-tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate |
| 利格列汀杂质23 | (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质24 | (S)-tert-butyl (1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate |
| 利格列汀杂质25 | (R)-7-(but-2-yn-1-yl)-8-(3-((7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)amino)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质26 | Linagliptin Acetamide |
| 利格列汀杂质27 | 8-bromo-7-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质28 | (R)-8-(3-aminopiperidin-1-yl)-7-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质29 | (R)-1-((4-methylquinazolin-2-yl)methyl)piperidin-3-amine |
| 利格列汀杂质30 | 1-(2-(((4-methylquinazolin-2-yl)methyl)amino)phenyl)ethanone |
| 利格列汀杂质31 | 8-((2-acetylphenyl)amino)-7-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质32 | 8-((2-acetylphenyl)amino)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质33 CAS号：93703-24-3 | 8-bromo-3-methyl-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质34 | 7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质35 | tert-butyl (7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)(piperidin-4-yl)carbamate |
| 利格列汀杂质36 | (S)-1-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)urea |
| 利格列汀杂质37 | (S)-N-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)acetamide |
| 利格列汀杂质38 | 8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-1-((4-((S)-2-(((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)propyl)quinazolin-2-yl)methyl)-3-methyl-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质39 | 7-(but-2-yn-1-yl)-3-methyl-8-(methylamino)-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质40 | 8-ethoxy-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质41 | 8-((R)-3-aminopiperidin-1-yl)-7-((Z)-3-(((R)-1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)amino)but-2-en-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione |
| 利格列汀杂质42 | 8-bromo-3-methyl-1,7-bis((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione |
| 利格列汀杂质43 CAS号：88203-04-7 | 2-((2-acetylphenyl)amino)acetonitrile |
| 利格列汀杂质44 CAS号：666816-98-4 | 8-bromo-9-(but-2-yn-1-yl)-3-methyl-1H-purine-2,6(3H,9H)-dione |
| 利格列汀杂质45 | (R)-9-(but-2-yn-1-yl)-8-(3-(1,3-dioxoisoindolin-2-yl)piperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,9H)-dione |
| 利格列汀杂质46 | 8-bromo-9-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,9H)-dione |
| 利格列汀杂质47 | (R)-8-(3-aminopiperidin-1-yl)-9-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,9H)-dione |
| 利格列汀杂质48 | 8-bromo-7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-3,7-dihydro-2H-purin-2-one |
| 利格列汀杂质49 | 8-bromo-7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-3H-purin-6(7H)-one |
| 利格列汀杂质50 | (R)-2-(1-(7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-2-oxo-3,7-dihydro-2H-purin-8-yl)piperidin-3-yl)isoindoline-1,3-dione |
| 利格列汀杂质51 | (R)-2-(1-(7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-6-oxo-6,7-dihydro-3H-purin-8-yl)piperidin-3-yl)isoindoline-1,3-dione |
| 利格列汀杂质52 | (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-3,7-dihydro-2H-purin-2-one |
| 利格列汀杂质53 | (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-3H-purin-6(7H)-one |
| 利格列汀杂质54 | (R)-8-(3-aminopiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-7-((4-methylquinolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione |
| 利格列汀杂质55 | N-(2-acetylphenyl)-2-bromoacetamide |
| 利格列汀杂质56 | tert-butyl ((3R)-1-(7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-6-oxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)carbamate |
| 利格列汀杂质57 | 8-((R)-3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-2-((4-methylquinazolin-2-yl)methoxy)-1,2,3,7-tetrahydro-6H-purin-6-one |
| 利格列汀杂质58 | tert-butyl (R)-(1-(7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-2-oxo-3,7-dihydro-2H-purin-8-yl)piperidin-3-yl)carbamate |
| 利格列汀杂质59 | (R)-8-(3-aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-6-((4-methylquinazolin-2-yl)methoxy)-3,7-dihydro-2H-purin-2-one |
| 利格列汀杂质60 | (R)-7-(but-2-yn-1-yl)-8-(3-hydroxypiperidin-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione |
| 利格列汀杂质61 | (R)-1-(1-(7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)piperidin-3-yl)urea |
| 利格列汀杂质62 | 8-bromo-9-(but-2-yn-1-yl)-3-methyl-3,9-dihydro-1H-purine-2,6-dione |
深圳远扬化学技术有限公司可现货供应各种杂质对照品，医药标准品：噁拉戈利杂质，邻乙酰水杨酸杂质，头孢唑啉钠杂质，氯美扎酮杂质，巴多昔芬杂质，美罗培南杂质，头孢丙烯杂质，乙酰氯芬酸杂质，尼美舒利杂质，保泰松杂质，沃拉帕赞杂质，雷洛昔芬杂质，甲氧氯普胺杂质，匹多莫德杂质，非洛地平杂质，度他雄胺杂质，甲巯咪唑杂质，达格列净杂质，依美斯汀杂质，帕罗西汀杂质，阿法替尼杂质，克唑替尼杂质，阿莫沙平杂质，贝那普利杂质，阿折地平杂质，伐昔洛韦杂质，伊潘立酮杂质，替莫唑胺杂质，喹硫平杂质，阿莫西林杂质，左旋多巴杂质，来那替尼杂质，普瑞巴林杂质，马来酸桂哌齐特杂质等，图谱证书齐全，纯度保证。
