联系信息

      奥贝胆酸由美国Intercept制药公司研发成功，是二十年来*研发用于治疗胆汁淤积性肝病的药物。奥贝胆酸属法尼醇X受体激动剂，通过活化法尼醇X受体，间接抑制细胞色素7A1（CYP7A1）的基因表达。由于CYP7A1是胆酸生物合成的限速酶，因此奥贝胆酸可以抑制胆酸合成，用于治疗原发性胆汁性肝硬化和非酒精性脂肪性肝病。   

       深圳远扬化学可提供奥贝胆酸申报所用全套杂质， 随货附CoA证书，HNMR，MS，HPLC图谱，纯度符合申报要求，奥贝胆酸杂质为我司优势杂质，长期备有库存，发货快。如需奥贝胆酸杂质相关详细信息，欢迎我司业务人员获取~

       除自主品牌杂质对照品外，我司还代理英国NIBSC标准品，美国剑桥CIL同位素标准品，美国NIST标准物质，欧洲标准局IRMM标准物质，加拿大TRC标准品，TLC标准品，MOLCAN标准品，NRC标准品等，欢迎洽谈。

附：奥贝胆酸杂质库存杂质列表：

Obeticholic Acid

(4R)-4-((3R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 1

(R)-4-((3R,5S,6R,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 2

(R)-4-((3R,5S,6S,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 3

(R)-4-((3R,5S,6S,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 4

(R)-4-((3R,5S,6S,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 5

(4R)-4-((3R,5S,6R,7R,9S,10S,13R,14S,17R)-6-ethyl-3-(((R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoyl)oxy)-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 6

(R)-4-((3R,5R,7S,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 7

(R)-4-((5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7-dioxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 8

(R)-methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

Obeticholic Acid Impurity 9

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 10

(R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 11

(R)-methyl 4-((3R,5S,6R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate